Endocrine Abstracts

Objectives: Orbital radiotherapy (OR) is the most commonly used second-line treatment for the severe forms of Graves’ orbitopathy (GO). The aim of our study was to assess the changes in the therapeutic response, ocular manifestations of GO and quality of life (QoL) during the first year after OR.Methods: The study involved 26 consecutive patients with active moderate-to-severe GO indicated for OR, 18 females, mean age 57±12.5. At baseline all pat...

IntroductionThyrotropin-receptor antibodies (TRAb) play a key role in the pathogenesis of Graves’ disease (GD) and Graves’ orbitopathy (GO) and are important for the diagnosis of both diseases. Elevated levels of immunoglobulin E (IgE) and antinuclear antibodies (ANA) were also found in GD patients. Smoking is a risk factor for GD and GO development and GO progression. We aimed to assess the associations between TRAb, IgE and ANA, and the prese...

Objectives: To evaluate the quality of life (QoL) in patients with differentiated thyroid cancer (DTC) by a validated thyroid-specific questionnaire and to identify factors with significant impact on the QoL.Methods: Two hundred DTC patients, treated in one tertiary center, were recruited in the study. One year after the thyroid surgery, they completed the QoL Cancer Survivor Instrument – Thyroid version questionnaire. The questionnaire assessed the...